本病是由破伤风杆菌引起的急性感染，其特征为随意肌间歇性强直性痉挛和咬肌痉挛，由此而被称为“牙关紧闭症”。系由破伤风杆菌外毒素导致的神经系统中毒性疾病，本病以进行性发展的肌肉强直为特征，伴有发作性加重，如不及时治疗，死亡率在10～40%左右。...
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